How To Take Levothyroxine Properly | Best Way To Take Thyroid Medication | When To Take Synthroid

By Brian Lemay 100 comments

Are you or someone you know getting the most out of your thyroid medication? well at the end of this video I promise you, you’re gonna know everything you need to know first a few facts about hypothyroidism which basically means low thyroid levels it’s quite common it affects 1 in 70 women and 1 in 1,000 men in the UK symptoms include fatigue, weight gain, sensitivity to the cold and many more so to restore thyroid levels in our body levothyroxine and similar medicines are prescribed and here’s how to take it for best results lots of patients ask me this and there’s actually quite a lot of conflicting advice online so as long as you haven’t been directed differently by a prescriber then here’s what I recommend tip 1 if you don’t take any medication first thing in the morning take it as soon as you wake up ideally 30 to 60 minutes before breakfast or any caffeinated drinks and this is my favourite mug and here’s a fun fact for everyone pharmacists love these kind of facts so if there’s any watching I hope you enjoy it so some studies show that food reduces the absorption of levothyroxine by up to 20% so that’s why we say take it on an empty stomach and that’s the fact I hope you enjoyed it tip 2 thyroid medication isn’t usually taken at night because some people find it difficult to fall asleep now it’s probably due to the relationship between the adrenal hormone cortisol and the hypothalamus pituitary axis which regulates all hormones in our body and that includes thyroid stimulating hormone tip 3 avoid taking your thyroid medication at the same time as your calcium supplements, iron supplements and antacids as these will also reduce its absorption but fear not you can still take these medicines but wait at least 4 hours after taking your thyroxine before you take them I’ve also left a link in the description below with all the
medicines that interact with levothyroxine so feel free to click on it tip 4 soya isn’t on that list but it can stop levothyroxine from working properly so if you do eat it regularly or take any soya supplements it’s worth letting your doctor know so they can do extra blood tests kelp isn’t on that list either but trust me it is a good list for medication interactions kelp contains iodine which can make an under-active thyroid worse so avoid eating it if you’re taking levothyroxine tip number 6 always let your pharmacist know that you taking levothyroxine especially when you’re starting a new medicine or you’re buying something over the counter because they can then check if there’s any interaction if you have any friends or family who take thyroid medication help them get the most out of their medicines by teaching them what you’ve learnt today or if that takes too long just like, share and tag them in hey guys thanks for watching this week’s
video make sure to click that like, follow or subscribe button now to stay
up to date with new weekly videos you’re going to know everything you need to know I hope you don’t mind you might be in the video ok with that? no come in its fine it doesn’t matter if you walk past sensitivity to the cold…….. if you can see him he’s got good muscles he works them out quite frequently but still not as good as my muscles


Nick C33444

Feb 2, 2018, 8:31 pm Reply

I have never clicked on the subscribe button so fast in my life

Donald Bowater

Jan 1, 2019, 7:32 pm Reply

Can you drink energy drinks

Rajula Haneefa

Jan 1, 2019, 2:09 pm Reply

Great vdo

November Lima

Jan 1, 2019, 7:33 pm Reply

So… my doc said I can't eat whole wheat bread or unpeeled fruits for FOUR HOURS after taking levothyroxine. Fact is even if I managed to skip the whole wheat toasts I would still eat an apple 3 hours after breakfast so.. I can't seem to fit it in. I do weight lifting I need my protein in every meal…. Would it be ok to take it after breakfast when my tummy starts crying for food again? Night would be ideal… but I don't have much time between last meal and bedtime… I'm seriously considering an alarm at 3am by this point.

April Snow

Jan 1, 2019, 11:27 am Reply

excellent video and well presented, thank you

Jen Gasis

Jan 1, 2019, 1:40 am Reply

Verry handsome 😘❤


Jan 1, 2019, 12:15 pm Reply

O what!

naresh krish

Feb 2, 2019, 2:12 am Reply

Sir i have hypothyroidism and I use thyroxine 100 mcg.
Will I take the tablet with water or normally i.e after taking tablet can i drink water?
After taking tablet will I sleep again?
Can I take fast food?
Please reply sir…

Offscreen Life Of Stars

Feb 2, 2019, 8:11 am Reply

I m taking milk tea after 1 hour having hypothyroidism medication I don't know is it OK or not

Mercy Hesed

Feb 2, 2019, 11:55 pm Reply

What about fiber… I start my day with water and glucomannan (a water-soluble fiber) to avoid fiber supplements with sugar and artificial sweeteners.

Roury queen

Feb 2, 2019, 1:47 am Reply

Could someone tell me why my hair is getting oily and greasy since I've taken thyroid medication?? ( my hair has always been dry and now I can handle it it's really greasy). Thank u ❤️

Mello Lev

Feb 2, 2019, 12:27 pm Reply

I was doing/avoiding everything you said until you said kelp!
I love kelp. I am so sad now.


Feb 2, 2019, 12:53 pm Reply

Its a permanent medicine or curable

Rick Banerjee

Feb 2, 2019, 7:47 pm Reply

Is it okay to take levothyroxine in the morning, but not eat anything for the next 4 or 5 hours?

the_geeky_ unicorn13

Feb 2, 2019, 9:38 pm Reply

I have been suffering from hypothyroidism for 10 years now. I have yet to find a dosage that works for me. I take it on a empty stomach I wait a hour sometimes more to eat. My numbers are either told high or too low….I gain weight with each new MCG I am prescribed. I just had to do labs again Friday to check my hormones this time because my doctor said my T4 was low (which never happened before). I am still asking to be put on armour but she is hesitant. I have visited every endocrinologist in my area they all say my numbers are "fine" but I still have all the symptoms. It is frustrating to have this illness.

Sahil Bijlani

Feb 2, 2019, 11:08 am Reply

I have hypothyroidism since 15 yrs can I take dose at night before going to bed

jay jay

Feb 2, 2019, 11:13 am Reply

always been puzzled by when to take different meds and why… thanks for the further clarification!


Feb 2, 2019, 6:10 am Reply

Love your energy, man.

Carol Benson

Feb 2, 2019, 5:10 am Reply

Thanks for video…going to subscribe now!


Feb 2, 2019, 9:00 pm Reply

you forgot the most important part. Do not drink milk after taking it, because it negates it's effects


Feb 2, 2019, 9:02 pm Reply

And what if my mornings are sometimes at 6 am, sometimes at 12 am ? Just take it whenever I wake up ?

Mary. A

Feb 2, 2019, 9:34 pm Reply

I have no thyroid because it was removed because of cancer I am on 200mg levothyroxine I feel dreadful fatigue, hair loss, scaly skin, weight gain. My tsh levels are out of whack!. Why in England are they not testing T3 and also is it true that T3 medication government can’t fund anymore because it’s an expensive drug???!!. I’m am one of those suffering because they won’t prescribe T3 like they use to. Thank you sorry fro the long comment.

TG&D. Ratcliffe

Feb 2, 2019, 9:45 am Reply

I have to get up in the middle of the night. That's when I take mine. Then go back to bed for an hour or two. Better uptake on very empty tum.

priscilla oduro

Feb 2, 2019, 1:53 pm Reply

I had been on 150mcg levothyroxine for 6 months since my tsh was 35.0p..I just went to do thyroid function test and my tsh is now 0.02 meaning I have become hyperthyroid..what is wrong ? Is it a side effect? Or my thyroid is now producing its sufficient hormones and the levothyroxine is now adding additional ones? Please help

Jay Dee

Mar 3, 2019, 12:30 am Reply

Can you take ashwaganda with levothyroxine?

Rikard Grandverger

Mar 3, 2019, 5:02 pm Reply

Im 14 and i have hypo 😑 any tips?

Pastel Landscapes

Mar 3, 2019, 3:51 am Reply

Started taking it this morning (subclinical hypothyroidism) while on intermittent fasting . Doctor said to take it after breakfast.. Im also on a weight loss program . Shouldve had doctors check up much earlier . Thanks for the vid :))

Prancing Pony

Apr 4, 2019, 9:03 am Reply

I didn’t realise about kelp! Arrgh stopping that now. Do you know if vitamin d3 and k2 interact with it? They are the only other suppliments I take

Punam Nandeshwar

Apr 4, 2019, 8:15 am Reply

When to do exercise ? Before or after taking thyroxine???


Apr 4, 2019, 12:45 pm Reply

Hi. Can I continue with my cod liver oil and turmeric supplements while taking this medication?

pharma care

Apr 4, 2019, 8:31 pm Reply

I am pharmacist I have also my own Youtube channel PHARMACARE support my channel✌️❤️🇮🇳🇮🇳


Apr 4, 2019, 1:14 am Reply

thank you for posting this video Abraham.
this may be the first med that i seen with instructions to take on empty stomach. lol
very helpful. thank you.

Jordan Brown

Apr 4, 2019, 3:20 am Reply

I just started this medication today, my doctor told me yesterday I had hypothyroidism after reviewing my blood test results, I forgot what a thyroid even was. Definitely shocking. Ugh, it’s caused me so far to feel extremely lethargic which is unfortunate because my job requires me to be alert. And I’m sorry if I’m ignorant but do we have to wait four hours after taking the pill to eat basically ANYTHING with iron in it? Or does it just refer to iron supplements? Isn’t iron in just about most foods? Basically I want to know what I’m allowed to eat 30 minutes after taking the pill. Thanks!

mikandra kate

Apr 4, 2019, 6:18 pm Reply

Hi! Love your videos! But I got a question. I'm a pharmacy student and I don't understand how taking an iodine supplements can make hypothyroidsm worse?

The Derpy Dino 2006

Apr 4, 2019, 5:01 am Reply

I take 25 g of levothyroxine a day I'm 13 Male and quite large how do I lose weight I gain weight so fast

sammy fitt

Apr 4, 2019, 9:56 am Reply

Is iodine not meant to be good for your thyroid …ie kelp ???

Alexa Dwyer

Apr 4, 2019, 9:25 pm Reply


I had radioactive iodine treatment and had to have this thing on top of me from head to toe and it felt like a magnet my eyes felt very pulled out and uncomfortable 😣 so please tell me if these are indecaters of Graves' disease? I was over active before all this

Alexa Dwyer

Apr 4, 2019, 9:27 pm Reply


What thyroid storm and symptoms and what can dr do ?

Tessa p

Apr 4, 2019, 1:26 am Reply

what about t3 medication should you stop this med 12 hours prior to getting labs or does that matter ?????????

Lubna Iftekhar

Apr 4, 2019, 9:17 am Reply

Hi , my tsh is normal and my gynae prescribed thyroxine to lose weight , I am obese atm after my first child’s birth no exercise or diet seemed to help. My question is will my body get used to of this med ? What will happen 1) if I fall pregnant while taking the med or ) when I stop taking thyroxin say after 3 months

Fiza Javid

May 5, 2019, 5:21 pm Reply

I couldn't see the medication interaction list because its only available for viewing in the UK :/


May 5, 2019, 12:25 pm Reply

I only like Synthroid the 'generic ' version makes me gain a LOT of fat , just letting you all know.

Elle Lean

May 5, 2019, 3:41 pm Reply

Thank you! It really helps in my OSCE POM Counselling!

chewie dawg

May 5, 2019, 4:09 pm Reply

from what i read thuroid meds make u gain more weight if taken with diabetes med ex janumet…what about if u work nyt shifts? is it ok to take it before u go to work instead of day time

Sam Buckel

May 5, 2019, 4:27 am Reply

I take .075 mg of this is that a lot for this drug?

Bean Tree

May 5, 2019, 5:13 pm Reply

Watched three videos and am immediately hooked! You're great! I have never heard of a prescribing pharmacist. I am in the U.S. and don't think we have this here. How long has there been prescribing pharmacists in the UK? Love the bloopers…adds levity…in just the right amount. You know your medicine! From a new subscriber!

Gegetsik Gulatyan

May 5, 2019, 8:00 am Reply


Mahima Ishu

May 5, 2019, 1:57 pm Reply

Can we have ACV when we have Hypothyroid. And if yes then can we take it empty stomach before taking thyroxine?

Elly Luquen music

Jun 6, 2019, 5:09 pm Reply

New subscriber here. I do exactly what you said. Thank you for sharing! By any chance, do you have any tips on losing weight with thyroid?


Jun 6, 2019, 7:05 am Reply

Do you know if Levothyroxine can be taken with Ashwagandha?

Chinnu k

Jun 6, 2019, 6:19 pm Reply

i startd my levothyroxine now 26 days.does inatke of levothyroxine causes any delay in periods to come..usulay have an 28 29 days periods interval..


Jun 6, 2019, 12:20 am Reply

so u dont suggest eating brazil nuts as it contains iodine while taking levo?


Jun 6, 2019, 2:38 pm Reply

Does protein powders affect this medication??

M. Nazir

Jun 6, 2019, 12:38 am Reply

I feel like your going to jump out of my phone after every cut scene

Mohammed NYC Vlogs

Jun 6, 2019, 11:24 pm Reply

Thank you

Nickie Haggart

Jun 6, 2019, 5:26 pm Reply


Monet Babazadeh

Jun 6, 2019, 1:17 pm Reply

Ah you’re the best

Erin Rose

Jun 6, 2019, 10:20 pm Reply

Thank you so much just to say everything you said to do I been doing the opposite , I'll try your way now , no-one tells you these things, first time I saw your channel , subbed

Melanie Petley

Jul 7, 2019, 1:44 pm Reply

I was 16 when diagnosed (I'm now 44) and was never sat down and really told anything from my GP other than the dosage! I originally went as I was exhausted at school all the time and then a lump came up on the front of my throat so I was originally tested for glandular fever (as I had not weight at all in fact I was a skinny underdeveloped child). I have annual blood tests but now I'm starting to get menopausal symptoms (my mum went through hers in her late 40s) so I'm wondering how this will effect my thyroid levels or vice versa.


Jul 7, 2019, 3:36 am Reply

Gotta love his energy


Jul 7, 2019, 1:47 am Reply

I been on levothyroxin 25mcg for over 2 months and I finally am getting period but I’m getting such bad cramps they feel like poop cramps not period ones but when I try to use the bathroom I don’t poop. So I don’t know what’s wrong but it’s affecting my work I’m having to leave early due to my cramping. Anyone have this problem?

Elaine Clements Finn

Jul 7, 2019, 8:20 pm Reply

My question is why is my hair still falling out and what component in Synthroid causes hair loss ??

Jovani Camacho

Jul 7, 2019, 9:01 am Reply

I thought iodine helps with thyroid?

Apostol Alex

Jul 7, 2019, 10:37 pm Reply

Is kelp still not recommended if i had my thyroid removed?

Jason Chipkin

Jul 7, 2019, 11:32 pm Reply

Iodine makes a slow thyroid worse?? That's contrary to everything I have researched recently. I'm replacing Levothyroxine with iodine supplement drops and ditching the big pharma meds.


Jul 7, 2019, 12:46 pm Reply

Useful, well spoken advice. Thank you!

Donnette onLive, Create, educate, empower

Jul 7, 2019, 2:57 pm Reply

I've taken minds around 4:30 am to 5 am and it's worked for me but my doctor's told me to take it early but I started taking it at specific time period because once I get dressed for work, I would forget so I made it a bathroom call moment.

Mandi Blackwell

Aug 8, 2019, 5:07 am Reply

As a pharmacy tech, I'd love to work with such a fun dude… zomg… lol, what if you take it in the morning but wind up falling back asleep? TT___TT for only like an hour? just to try to keep it in the morning and away from food………


Aug 8, 2019, 4:05 pm Reply

I'm on Levothyroxine and Liothyronine. I take the Levo at night and the Lio in the morning, I also take fibromyalgia medication in the morning. I usually have coffee pretty much first thing in the morning because it helps get rid of my morning headache.

Rayyan25 Khan

Aug 8, 2019, 9:44 pm Reply

I'm facing too much hair loss after hypothyroid my ferritin level is low and also white hair problem . You don't talk about it


Aug 8, 2019, 6:00 am Reply

It seems I've been eating too soon.

Soha Bhayo

Aug 8, 2019, 5:19 pm Reply

After 30..40min of taking my thyroid medicine should I take apple cider vinegar?

pam d

Aug 8, 2019, 8:52 pm Reply

Hold up so if I take metformin in the morning and pro vitamin d plus and my linagliptin in the morning should I not take my levothyroxine at same time ??

Tracy Ann

Aug 8, 2019, 9:42 pm Reply

I take Levothroxine for my under-active thyroid. Is it safe to take Ashwaganda while taking my Thyroid medication?

Mary. A

Sep 9, 2019, 8:12 am Reply

Is there alternative to levothyroxine the side effects that I’m experiencing are dreadful weight gain, hair loss, dry skin, bad nails. What other thyroid meds are available on nhs?!

Gabriela Recillas

Sep 9, 2019, 3:54 am Reply

Heck I was surprised to hear Iodine interacts negatively with Levothyroxine! I was under the impression that it helped! Thanks for the tip!

Sehrish Ramzan Sehrishramzan

Sep 9, 2019, 6:21 pm Reply

i have take always morning tab thyronorm


Sep 9, 2019, 11:55 am Reply

I take it just as you describe to the letter, but I'll give you a FACT about this medication in MY case – it GIVES ME depression and makes me angry.
I had the does lowered from 100 to 75mg, but I get depression.
As soon as I stop it the depression disappears.
I cannot speak for everyone, but it obviously des not suit me at all.
What is the point being a little thinner if I am to be made depressed to the point of wishing I were dead?
For me personally this medicine is evil.

akira kazmi

Sep 9, 2019, 4:53 am Reply

I thought iodine supported the thyroid? Isn't Kelp rich in iodine?


Sep 9, 2019, 1:34 pm Reply

How to buy cox thyroxine medicine i from korea

Jonathan Fisher

Sep 9, 2019, 4:26 pm Reply

I keep reading many places you should try to take this prescription two hours after eating a meal, not 1 hour like the video suggest.

shambli dsouza

Sep 9, 2019, 10:36 am Reply

Hi my TSH is 28.01 and I'm taking eltroxin 50mg is it the right dose pls advice. Regards


Sep 9, 2019, 1:58 pm Reply

He makes things funny and fun, which makes it more tolerable to sit thru. Most of the time the 'dry as a bone' medical person has me yawning so much I switch it off. One thing he didn't cover and nobody seems to… HOW MUCH WATER SHOULD YOU TAKE WITH YOUR THYROID PILL? Also, can you take thyroid med with diet soda, or flavored water etc?


Sep 9, 2019, 2:00 pm Reply

Also, I thought KELP was good for an underactive thyroid? Because kelp has thyroid stimulating affects?


Oct 10, 2019, 6:12 pm Reply

Hi Abraham, My thyroid gland was removed 1.5 years ago. Usually I wake up every morning, take a pill then sleep again for an hour and then wake up. Recently, often I am feeling bad and tired, sometimes concentration (mental) on a subject is difficult for me, and even at the morning when I wake up after sleeping 8 hours I am still tired and I can not feel as energetic and fresh as I was before surgery. Thus I would like to know whether can sleeping after taking pill cause such effects?Thanks


Oct 10, 2019, 4:19 pm Reply

Pretty sure I have hypothyroidism. I pretty much have to go to the doctor for bloodwork, or is there over the counter medicine I can take?

Healthy Together

Oct 10, 2019, 2:51 am Reply

Could you please tell me if levothyroxine has any issue with fiber intake? Also pls enlighten me whether I must have my breakfast within 2 hours of medication or that does not matter? Can stomach acidity causes any issue with levothyroxine absorption? Thank you so much…waiting for your reply.

Lilly V Gutierrez

Oct 10, 2019, 12:50 am Reply


Vanessa Silva

Oct 10, 2019, 4:14 am Reply

So ppl that have hypothyroidism can’t take kelp or any iodine supplements or foods ? Like sushi ?
If No why please
I have hypo and I really wanna know if I need to avoid iodine


Oct 10, 2019, 11:28 pm Reply

Do digestive enzymes help better absorption of thyroid meds? If so is it better to take it at the same time?


Nov 11, 2019, 7:13 pm Reply

How to take levothyroxine properly: throw it in the bin unless you are also on some form of T3 and are using it as a combination therapy. Most people on levo still have hypo symptoms because the body needs more than T4 and conversion is hampered (ironically) by a low TSH. This excellent paper explains the issues with Levo very well:


Nov 11, 2019, 4:55 am Reply

Hes wrong about iodine making an underactive thyroid worse

Jazmin Arballo

Nov 11, 2019, 6:34 pm Reply

I was born with hypothyroidism. I have been told many of times that iodine is good when you have hypothyroidism.

KK Corleone

Nov 11, 2019, 5:22 am Reply

Hi Does It Help Taking The Medication Everyday at a specific Time???

Psalm 122:6 S

Nov 11, 2019, 1:09 am Reply

Thank you for the information – much needed and much appreciated.

Seoun Crestha

Nov 11, 2019, 7:35 am Reply

What about the Apple cider vinegar? Is it ok to have Apple cider vinegar while having the levothyroxin?

نذير يوسف

Nov 11, 2019, 8:46 pm Reply

I subscribed so fast.


Nov 11, 2019, 1:07 pm Reply

The weird thing for me is I cant take levothyroxadine in the morning it knocks me out asleep .I hav to take it at bedtime.

Sanu Stha

Nov 11, 2019, 3:11 pm Reply

Can we take medicine with water?


Nov 11, 2019, 7:23 am Reply

When’s the best time to take my multivitamin? Say, I ate after 30 mins. after taking levothyroxine, can I take my multivitamin after?

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